GASZTROENTEROLÓGIA ONKOLÓGIA MOLEKULÁRIS BIOLÓGIA (GOMB) 2011 GASTROENTEROLOGY ONCOLOGY MOLECULAR BIOLOGY (GOMB) 2011

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1 GASZTROENTEROLÓGIA ONKOLÓGIA MOLEKULÁRIS BIOLÓGIA (GOMB) 2011 GASTROENTEROLOGY ONCOLOGY MOLECULAR BIOLOGY (GOMB) 2011 NEW EUROPEAN INITIATIVES IN COLORECTAL CANCER SCREENING BUDAPEST-DECLARATION MOLECULAR MEDICINE IN GI ONCOLOGY EAGE POSTGRADUATE COURSE 2011 NEMZETKÖZI KONGRESSZUSOK INTERNATIONAL CONGRESSES BUDAPEST MÁJUS BUDAPEST MAY, 2011 HELYSZÍN: NOVOTEL CENTRUM VENUE: HOTEL NOVOTEL HOTEL BUDAPEST CENTRUM BUDAPEST 1088 Budapest, Rákóczi út Rákóczi str , H-1088 Budapest

2 Congress President Prof. Dr. Zsolt Tulassay Semmelweis Medical University, 2 nd Department of Internal Medicine Budapest, Hungary tulassay@bel2.sote.hu Congress Secretary Dr. László Herszényi Semmelweis Medical University, 2 nd Department of Internal Medicine Budapest, Hungary hersz@bel2.sote.hu Congress Bureau Mr. Károly Bagdi, managing director Convention Budapest Ltd. kbagdi@convention.hu Address: H-1461 Budapest, P.O.Box 11. Phone: , -85, -86, ext Fax: Venue of the Congress Novotel Centrum Hotel 1

3 Fő szponzor: Bayer Hungaria Kft. Kiállítók, támogatók: Activity Group Raiffeisen Bank Amgen Kft. Gasztroenterológiai Szakmai Kollégium Magyar Gasztroenterológai Társaság Novartis Hungária Kft. REOF Kft. Roche Magyarország Kft. Sanofi-Aventis Zrt. Köszönjük támogatásukat. 2

4 GASZTROENTEROLÓGIA ONKOLÓGIA MOLEKULÁRIS BIOLÓGIA (GOMB) 2011 I. INTERDISZCIPLINARIS KONGRESSZUS GASTROENTEROLOGY ONCOLOGY MOLECULAR BIOLOGY (GOMB) st INTERDISCIPLINARY CONGRESS A kongresszus elnöke: Prof. Dr. Tulassay Zsolt akadémikus, egyetemi tanár Congress President: Professor Zsolt Tulassay, member of Hungarian Academy of Sciences Program május 26. (csütörtök) May 26, 2011 (Thursday) Regisztráció Registration A daganat keletkezés molekuláris genetikája és pathológiája Molecular genetics and pathology of carcinogenesis Üléselnök-Chair: Matolcsy András A daganatképződés molekuláris alapjai Molecular basis of carcinogenesis Matolcsy András A daganatok növekedése és terjedése Tumor growth and progression Tímár József Vastagbél daganatok molekuláris eltérései Molecular changes in colorectal cancer Molnár Béla Kávészünet Coffee break A daganatok kezelésének új szempontjai New aspects of oncological therapy Üléselnök-Chair: Bodoky György A colorectalis daganatok célzott kezelése Targeted therapy of colorectal cancer Boér Katalin A célzott kezelés hatásának előrejelzése Predictors of the effect of targeted therapy Schwab Richárd Biológiai kezelés Biological therapy Bodoky György 3

5 GASZTROENTEROLÓGIA ONKOLÓGIA MOLEKULÁRIS BIOLÓGIA (GOMB) 2011 I. INTERDISZCIPLINARIS KONGRESSZUS GASTROENTEROLOGY ONCOLOGY MOLECULAR BIOLOGY (GOMB) st INTERDISCIPLINARY CONGRESS A gyomorrák kórisméjének és kezelésének molekuláris alapjai Gastric cancer: molecular basis of diagnosis and therapy Üléselnök-Chair: Herszényi László A gyomorrák új pathológiai szemlélete Gastric cancer: new aspects of pathological approach Micsik Tamás Az endoscopos kórisme új szempontjai New aspects of endoscopic diagnosis Juhász Márk A gyomorrák célzott kezelése Targeted therapy of gastric cancer Dank Magdolna Ebédszünet Lunch A bélrendszer daganatainak molekuláris biológiája Molecular biology of intestinal tumors Üléselnök-Chair: Pápai Zsuzsa Rákelőző állapotok Precancerous lesions Zalatnai Attila A vastagbél daganatok kórisméje és kezelése Diagnosis and treatment of colorectal cancer Pintér Tamás A GIST molekuláris pathológiája Molecular pathology of GIST Sápi Zoltán A GIST tumorok korszerű kezelése Current treatment of GIST Pápai Zsuzsa Kávészünet Coffee break 4

6 GASZTROENTEROLÓGIA ONKOLÓGIA MOLEKULÁRIS BIOLÓGIA (GOMB) 2011 I. INTERDISZCIPLINARIS KONGRESSZUS GASTROENTEROLOGY ONCOLOGY MOLECULAR BIOLOGY (GOMB) st INTERDISCIPLINARY CONGRESS Gastroentero-pancreatikus daganatok molekuláris biológiája Molecular biology of gastroentero-pancreatic tumors Üléselnök-Chair: Rácz Károly GEP tumorok molekuláris diagnosztikája Molecular diagnosis of GEP tumors Zalatnai Attila NET tumorok új kezelési lehetőségei New therapeutic opportunities of NET tumors Uhlyarik Andrea GEP tumorok peptid radionuklid kezelése Radionuclid peptide therapy of GEP tumors Igaz Péter Neuroendokrin tumor regiszter Neuroendocrine tumor-register Igaz Péter GEP-tumor magyarországi regiszter: tanácsadó testület ülése Hungarian GEP-tumor register: Advisory Board Meeting 5

7 HEPATOCELLULARIS CARCINOMA KORSZERŰ SZEMLÉLETE PATH TUDOMÁNYOS ÜLÉS KEREKASZTAL KONFERENCIA CURRENT APPROACH OF HEPATOCELLULAR CARCINOMA PATH SCIENTIFIC MEETING ROUNDTABLE CONFERENCE A kongresszus elnöke: Prof. Dr. Tulassay Zsolt akadémikus, egyetemi tanár Congress President: Professor Zsolt Tulassay, member of Hungarian Academy of Sciences Program május 27. (péntek) May 27, 2011 (Friday) szekció 1 st section Üléselnök-Chair: Schaff Zsuzsa Epidemiológia, klinikai tünetek Epidemiology, clinical picture Lengyel Gabriella Kóreredet, patológia Pathophysiology and pathology Schaff Zsuzsa Képalkotó kórisme Imaging diagnosis Jakab Zsuzsa Kávészünet Coffee break szekció 2 nd section Üléselnök-Chair: Bodoky György Kezelési módok áttekintése Overview of therapeutic approaches Dank Magdolna Szisztémás kezelés Systemic therapy Bodoky György Intervenciós kezelés Interventional therapy Doros Attila Sebészeti kezelés Surgical therapy Nemes Balázs 6

8 HEPATOCELLULARIS CARCINOMA KORSZERŰ SZEMLÉLETE PATH TUDOMÁNYOS ÜLÉS KEREKASZTAL KONFERENCIA CURRENT APPROACH OF HEPATOCELLULAR CARCINOMA PATH SCIENTIFIC MEETING ROUNDTABLE CONFERENCE Ebédszünet Lunch szekció 3 rd section Üléselnök-Chair: Szalay Ferenc A májátültetés előkészítése Preparation of liver transplantation Szalay Ferenc Májátültetés általános sebészi szempontjai Surgical aspects of liver transplantation Langer Róbert Májátültetés HCC-ben Liver transplantation in HCC Fehérvári Imre A betegek rehabilitációja és gondozása Rehabilitation & follow up of patients after liver transplantation Gerlei Zsuzsa szekció 4 th section Üléselnök-Chair: Tulassay Zsolt State of art lecture: A HCC molekuláris biológiája Molecular biology of HCC Szabó Gyöngyi Kávészünet Coffee break 7

9 NEW EUROPEAN INITIATIVES IN COLORECTAL CANCER SCREENING BUDAPEST-DECLARATION Official program during the Hungarian Presidency of the Council of European Union Under the auspices of UEGF, EAGE and the Hungarian Society of Gastroenterology Sajtótájékoztató Press Conference (Zsolnay III. terem) Üléselnökök-Chairs: Wittmann Tibor, Herszényi László, Tulassay Zsolt Témák Topics: 1. Budapest Kiáltvány : Új európai kezdeményezések a vastagbélrák szűrésben Budapest Declaration New European initiatives in colorectal cancer screening 2. A soron következő, Magyar Gasztroenterológiai Társaság 53. Nagygyűlésének fontosabb témái Main topics of the upcoming Congress of Hungarian Society of Gastroenterology 8

10 NEW EUROPEAN INITIATIVES IN COLORECTAL CANCER SCREENING BUDAPEST-DECLARATION Official program during the Hungarian Presidency of the Council of European Union Under the auspices of UEGF, EAGE and the Hungarian Society of Gastroenterology Representative of Ministry of National Resources: András Jávor, State Secretary Program May 27, 2011 (Friday) Chairmen: Jaroslaw Regula, Reinhold Stockbrügger, Zsolt Tulassay, Tibor Wittmann Risk factors and primary prevention in colorectal cancer Daisy Jonkers (Maastricht, The Netherlands) Colorectal cancer screening: Population-based and/or opportunistic Reinhold Stockbrügger (Ferrara, Italy) Primary detection of colorectal cancer with FOBT-FIT results of piloting screening programs in Hungary László Herszényi (Budapest, Hungary) Molecular biology and carcinogenesis of sporadic colorectal cancer Béla Molnár (Budapest, Hungary) Peripheral blood and stool DNA Tests in colorectal cancer screening Jean-Christophe Saurin (Lyon, France) Off lebel use and patients safety Sándor Kerpel-Frónius (Budapest, Hungary) Coffee break Quality indicators of screening colonoscopy Jaroslaw Regula (Warshaw, Poland) Screening colonoscopy versus CT-colonography Alberto Malesci (Milano, Italy) Targeted therapy in colorectal cancer T. Pintér (Győr, Hungary) Colorectal cancer: a multidisciplinary approach Béla Teleky (Wien, Austria) Budapest Declaration on colorectal cancer screening Tibor Wittmann (Szeged, Hungary) 9

11 NEW EUROPEAN INITIATIVES IN COLORECTAL CANCER SCREENING BUDAPEST-DECLARATION Official program during the Hungarian Presidency of the Council of European Union Under the auspices of UEGF, EAGE and the Hungarian Society of Gastroenterology Colorectal cancer (CRC) is the second most common newly diagnosed cancer and the second most common cause of death in the EU. There are approximately newly detected cases in Europe and more than deaths due to CRC each year. CRC is an enormous health and economic burden. Many of cancer-associated deaths could be avoided through early detection by high-quality colorectal screening programmes. The clear advantage of CRC screening is that can detect cancer at an early stage. This can result in a better prognosis with less expensive oncologic therapy and finally, lowers mortality rates. Under the auspices of UEGF, EAGE, Hungarian Society of Gastroenterology and Hungarian College of Gastroenterology the Budapest Declaration (2011) will be put forward by European experts in the field of colorectal cancer. This important Meeting is an accepted official scientific programme during the Hungarian Presidency of the Council of European Union. It follows the Munich Declaration (2001), the Brussels Declaration (2007), the Transatlantic Declaration (2009), the Barcelona Declaration (2010), the written declaration of CRC screening, a joint initiative with European Parliamentarians, coordinated by the UEGF, and finally, The European Guidelines for quality assurance in CRC screening and diagnosis. Budapest Declaration together with the above mentioned previous declarations aims to urge the national and supranational healthcare decision makers to launch new Europe-wide initiatives to establish high-quality CRC programmes to achieve optimal efficiency in CRC screening. Budapest, May Reinhold Stockbrügger Chair Public Affairs Committee UEGF Peter Dite President EAGE Tibor Wittmann President Hungarian Society of Gastroenterology László Herszényi Secretary-General Hungarian Society of Gastroenterology Zsolt Tulassay President of the Congress 10

12 EUROPEAN ASSOCIATION FOR GASTROENTEROLOGY AND ENDOSCOPY Dear colleagues and friends, The EAGE is one of the founding organizations of the contemporary United European Gastroenterological Federation. It is the aim of the EAGE to present interactive and highly professional teaching events on diseases of the digestive system and to provide aducational exchange platforms to further expand and update the knowledge in Gastroenterology. Diseases of the digestive system are complex and often require a multidisciplinary approach. Our goal therefore is to structure our education in connection with specialists of pathology, radiology, immunology, surgery, oncology, genetics etc. With emphasis on case management as well as specific topics, including aspects of interdisciplinary medicine, we believe that our EAGE postgraduate courses guarantee a well-rounded education in the highly specialized world of medicine. The EAGE offers individual membership through EAGE course participation and members are eligible for a two-year online subscription of the Digestive Disease Publication. Please also visit our website for updates and details. EAGE Council 11

13 EUROPEAN ASSOCIATION FOR GASTROENTEROLOGY AND ENDOSCOPY The European Association for Gastroenterology and Endoscopy is a forum for the exchange of ideas & knowledge in Gastroenterology and Hepatology, particularly through promotion of postgraduate education, funding of research and training. To achieve its goal, the EAGE initiates: Organisation of postgraduate courses with an emphasis on clinical gastroenterology Sponsorship of special training in research Stimulation of young investigators through prizes for research achievements Fostering of European links by encouraging membership from all European countries and by helping local groups to organize meetings and courses 12

14 MOLECULAR MEDICINE IN GI ONCOLOGY EAGE POSTGRADUATE COURSE Program May 28, 2011 (Saturday) Course directors: P. Malfertheiner, GNJ. Tytgat, Z. Tulassay Session I. Translational Medicine and Methodology Chairs: P. Malfertheiner, F. Farinati 1. Novel prognostic biomarkers A. Malesci, Italy 2. Signal transduction therapy in G.I. tumors G. Kéri, Hungary 3. Single organ screening or integrated cancer prevention R. Stockbrügger, Italy 4. Microsatellite instability and therapeutic consequences in colorectal cancer L. Laghi, Italy 5. Inflammation, proteinases, tumor progression L. Herszényi, Hungary Coffee Session II. Solid tissue cancers Chairs: P. Dite, G. Kreis 1. Molecular hepatic carcinogenesis G. Szabó, USA 2. Molecular targeted therapy in hepatic cancer F. Farinati, Italy 3. Pancreatic carcinogenesis P. Dite, Czech Republic 4. Neuroendocrin tumors and targeted therapy G. Kreis, Austria 13

15 MOLECULAR MEDICINE IN GI ONCOLOGY EAGE POSTGRADUATE COURSE Lunch Session III. Upper gastrointestinal tract Chairs: L. Lazebnik, G. Szabó 1. Molecular markers in gastric premalignant lesions M. Leja, Latvia 2. Molecular abnormalities in Helicobacter related gastric carcinogenesis P. Malfertheiner, Germany 3. Stem cell therapy in GI diseases L. Lazebnik, Russia Coffee Session IV. Colon Molecular innovations of GI cancer managment Chairs: J. Regula, L. Herszényi 1. Family history in the evaluation of CRC J. Regula, Poland 2. Molecular signatures at colorectal cancer development B. Molnár, Hungary 3. Genomics of GI cancers I. Peták, Hungary 14

16 EUROPEAN ASSOCIATION FOR GASTROENTEROLOGY AND ENDOSCOPY Outlook for Postgraduate Courses in 2012: February 2012 Muscat, Oman April 2012 Prague, Czech Republic June 2012 Treviso, Italy October 2012 Krakow, Poland November 2012 Berlin, Germany Please visit our website for updates, further details and dates. 15

17 EUROPEAN ASSOCIATION FOR GASTROENTEROLOGY AND ENDOSCOPY EUROPEAN Bridging M e e t i n g in Gastroenterology & Berlin, Germany November 10 12,